2 Jan 2006 pfh   » (Master)

Commenced taking bupropion. Modafinil has been pooping out on me.

Bupropion is a re-uptake inhibitor for noradrenaline and dopamine. Being able to take any drug that buggers with dopamine directly is unusual. Most anti-depressants, for example, target seratonin and/or noradrenaline. Dopamine is taboo.

I decided to take bupropion because there seems to be some link between dopamine and sociability. A long shot. The last in a series of long shots (in one case asking more of a friend than is fair -- on reflection, doomed to fail whatever they said, it would not have fixed the core problem, just sucked them into it too).

Initial observations: yes, I do seem to be somewhat more sociable. Possibly placebo effect. Also, possibly a stimulant effect (probably noradrenaline related). So take the following comments with a pinch of salt.

Seems like I can make relevant associations more quickly, eg recall names -- I would say this is the major factor affecting sociability. In this respect, it feels similar to the modafinil.

Also, everything gets a bit "glowy". I am reminded of nicotine. I was hoping for this, so possibly a placebo effect.

Slight feeling of fug typical of anti-depressants.

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