Autopackage is Yet Another Packaging System.
As if there weren't already enough of those. The unique feature it has is that it is distribution neutral. You can make one autopackage and install it on Red Hat, SuSE, and Ubuntu.
The LSB tries to accomplish the same thing both by standardizing a directory structure and by standardizing a package format + a set of standard packages.
Unfortunately, it is not enough. Applications need to integrate well with Gnome and KDE these days. They also need more binary portability than LSB can easily provide.